Life-Threatening Infectious Complications in Sickle Cell Disease: A Concise Narrative Review
Sickle cell disease (SCD) results in chronic hemolytic anemia, recurrent vascular occlusion, insidious vital organ deterioration, early mortality, and diminished quality of life.Life-threatening acute physiologic crises may occur on a background of progressive diminishing vital organ function.Sickle hemoglobin polymerizes in the deoxygenated state,